Contacts Centre for Environmental Biology



CBA research group(s):

Experimental Evolution

Personal webpage

Team webpage

Pedro Simões

Main Research Interests

My main research interests concern Evolutionary Biology, Evolutionary Genetics and Experimental Evolution. Most of my research has been focussing on the analysis of processes and patterns during adaptation to a new environment as well as its underlying genetic basis. I am also interested in understanding clinal patterns of genetic variation specifically addressing the adaptive role of inversion polymorphisms in Drosophila and the genetic content of these chromosomal arrangements.


Academic Qualifications

- 2007 - PhD in Biology (Evolutionary Biology) (University of Lisbon)
- 2002 – Degree in Biology (University of Lisbon)


Recent Publications

Bárbaro M., Mira M. S., Fragata I., Simões P., Lima M., Lopes-Cunha M., Kellen B., Santos J., Varela S.A.M., Matos M.* & Magalhães S.* 2015. Evolution of mating behavior between two populations adapting to common environmental conditions. Ecology and Evolution 5(8):1609–1617 [* joint last authors]

Matos M., Simões P., Santos M.A., Seabra S.G., Faria G.S., Vala F., Santos J. & Fragata I. 2015. History, chance and selection during phenotypic and genomic experimental evolution: replaying the tape of life at different levels. Front. Gene. 6:71. doi: 10.3389/fgene.2015.00071​

Fragata I., Lopes-Cunha M.,  Bárbaro M., Kellen B.,  Lima M., Santos M. A., Faria G. S., Santos M., Matos M. &  Simões P. 2014. How much can history constrain adaptive evolution? A real time evolutionary approach of inversion polymorphisms in Drosophila subobscura. Journal of Evolutionary Biology 27(12):2727-2738.

Fragata I., Simões P., Lopes-Cunha M., Lima M., Kellen B.,  Bárbaro M., Santos J., Rose M. R., Santos M. & Matos M. 2014. Laboratory Selection Quickly Erases Historical Differentiation. PLoS ONE 9(5):e96227.

Santos J., Pascual M., Simões P., Fragata I., Rose M.R. & Matos M. 2013. Fast evolutionary genetic differentiation during experimental colonizations. Journal of Genetics 92(2):183-194.

Santos J., Pascual M., Simões P., Fragata I., Lima M., Kellen B., Santos M., Marques A., Rose M.R. & Matos M. 2012. From nature to the lab: the impact of founder effects on adaptation. Journal of Evolutionary Biology 25:2607-2622.

Simões P. Calabria G., Picão-Osório J., Balanyà J. & Pascual M. 2012. The genetic content of chromosomal inversions across a wide latitudinal gradient Plos One 7(12):e51625.

Simões P., Pascual M., Coelho M. & Matos M. 2010. Divergent evolution of molecular markers during laboratory adaptation in Drosophila subobscura. Genetica 138:999-1009.

Santos M., Fragata I., Santos J., Simões P., Marques A., Lima M. & Matos M. 2010. Playing Darwin. Part B. 20 years of domestication in Drosophila subobscura. Theory in Biociences 129:97-102.

Simões P., Santos J. & Matos M. 2009. Experimental Evolutionary Domestication. Chapter 5. In Experimental Evolution: Concepts, Methods, and Applications of Selection Experiments, Garland T. & Rose M. R. (eds.), California University Press, 89-110.

Simões P., Pascual M., Santos J., Rose M.R. & Matos M. 2009. Correction: Evolutionary dynamics of molecular markers during local adaptation: a case study in Drosophila subobscura BMC Evolutionary Biology 9:133.

Simões P., Pascual M., Santos J., Rose M.R. & Matos M. 2008. Evolutionary dynamics of molecular markers during local adaptation: a case study in Drosophila subobscura. BMC Evolutionary Biology 8:66.

Simões P., Santos J., Fragata I., Mueller L.D., Rose M.R. & Matos M. 2008. How repeatable is adaptive evolution? The role of geographical origin and founder effects in laboratory adaptation. Evolution 62(8):1817-1829.

Simões P., Rose M. R., Duarte A., Gonçalves R. & Matos M. 2007. Evolutionary domestication in Drosophila subobscura. Journal of Evolutionary Biology 20(2):758-766.

Matos  M., Simões P., Duarte A., Rego C., Avelar T. & Rose M. R. 2004. Convergence to a novel environment – comparative method versus experimental evolution. Evolution 58 (7):1503-1510.


Ongoing projects

PTDC/BIA-BIC/2165/2012 (FCT) - "History, chance and selection during local adaptation: a genome-wide analysis" - team member. 

Post-Doctoral Research Grant (BPD): "Gene expression patterns during adaptation: an experimental evolution study in D. subobscura" financed by FCT (ref SFRH/BPD/86186/2012).